Magnesium deficiency affects an estimated 50% of Americans. Magnesium glycinate is the most bioavailable and gentle form, supporting sleep, muscle relaxation, stress, and hundreds of enzymatic reactions. We rank the top 5 supplements.
Why We Reviewed Roundup
Magnesium glycinate is bound to glycine, an amino acid with its own calming properties. This makes it superior to cheaper forms like magnesium oxide for sleep and anxiety support.
✅ Pros
- Highly bioavailable form
- Supports sleep quality
- Reduces muscle cramps
- May help with anxiety
- Gentle on digestion
❌ Cons
- More expensive than magnesium oxide
- Large capsules
- Takes 2–4 weeks for full effect
Key Ingredients
- #1 Thorne Magnesium Bisglycinate
- #2 Life Extension Magnesium (Glycinate)
- #3 KAL Magnesium Glycinate
- #4 Nutricost Magnesium Glycinate
- #5 NOW Foods Magnesium Glycinate
Who Is This For?
Poor sleepers, those under chronic stress, athletes with muscle cramps, and anyone not getting enough magnesium from diet.
Check Current Price on Roundup
Find our top magnesium glycinate picks through the links above.
View Best Price →Price & Value
Range: $15–$35 for 30–90 day supply depending on brand.
Our Verdict
Magnesium glycinate is one of the most evidence-backed supplements for sleep and stress. Thorne's version is our top pick for purity and bioavailability. We give it a N/A/5 and recommend it for poor sleepers, those under chronic stress, athletes with muscle cramps, and anyone not getting enough magnesium from diet.